

Proteins.
Invented by nature,
perfected by Scala.


ABOUT SCALA
We provide our partners a unique one-shot computational solution to dramatically increase the value and accelerate the development of proteins into commercial products
Nature provides solutions to some of the biggest challenges facing humanity. The pharmaceutical, chemical and sustainability industries are harnessing nature’s molecular machines — enzymes, antibodies, and other proteins — to provide life-saving drugs and environmental-friendly processes that generate the products our societies need.
But natural proteins lack the resilience and specificity that modern medicine and industry require.
We combine evolutionary analysis, atomistic protein design calculations, and AI to design proteins that exhibit superior properties. Our solution is based on more than a decade of research at the Weizmann Institute of Science and in collaboration with dozens of labs around the world.
Our strategy yielded the first one-shot design approaches to be validated across vaccine immunogens, industrial and therapeutic enzymes, therapeutic antibodies, molecular probes, membrane channels, and more.
PRODUCTS
PROTEIN STABILITY & EXPRESSION
01
Improve production yields & expression of complex proteins in simple organisms
Increase thermostability
Increase resilience to organic solvents, pH, etc.
Increase shelf life
Reduce aggregation
ENZYME
ACTIVITY
02
Improve catalytic activity
Increase enzyme specificity



PROTEIN-PROTEIN INTERACTIONS
03
Future Product
Protein affinity engineering
MEMBRANE PROTEINS
04
Future Product
Improve expression & thermostability
ANTIBODY OPTIMIZATION
05
Future Product
Humanization
Stabilization
Dr. Adi Goldenzweig
Co Founder & CTO
Creative Strategist









THE FOUNDING TEAM



Dr. Adi Goldenzweig
Co-founder & CTO



Dr. Ravit Netzer
Co-founder & CEO



Prof. Sarel Fleishman
Chief Scientist
Our founding team has over a decade of experience developing cutting-edge protein design methods.
We established Scala to elevate protein design to the scale and reliability that are needed by the biotechnology and biopharmaceutical industries.
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