Nature provides solutions to some of the biggest challenges facing humanity. The pharmaceutical, chemical and sustainability industries are harnessing nature’s molecular machines — enzymes, antibodies, and other proteins — to provide life-saving drugs and environmental-friendly processes that generate the products our societies need.

But natural proteins lack the resilience and specificity that modern medicine and industry require.
We combine evolutionary analysis, atomistic protein design calculations, and AI to design proteins that exhibit superior properties. Our solution is based on more than a decade of research at the Weizmann Institute of Science and in collaboration with dozens of labs around the world.

Our strategy yielded the first one-shot design approaches to be validated across vaccine immunogens, industrial and therapeutic enzymes, therapeutic antibodies, molecular probes, membrane channels, and more.